Clustering
Expression profiles
Represent change in expression from baseline. Can plot as line graph, or as colour strips. Useful for displaying thousands of genes.
Expect that genes with similar expression profiles have similar functions or work in same process.
Clustering
- Choose distances measure (eg. euclidean, correlation)
- Choose clustering method (hierarchical, divisive)
- Choose linkage method (single, complete, average)
- Group together two closest clusters
- Repeat